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Bilayer sustained release floating metoprolol tartrate tablet: formulation, evaluation and optimization

  • At: 2011 FIP Congress in Hyderabad (India)
  • Type: Poster
  • By: SHRESTHA, Rajan (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
  • Co-author(s): Bhattarai, Manoj (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
    Maharjan, Sanju (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
    Nepal, Mahesh Raj (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
    Pradhananga, Binita (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
    Ranjit, Sabina (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
    Budhathoki, Uttam (Kathmandu University, School of Science, Department of Pharmacy, Dhulikhel, Nepal)
  • Abstract:

    Aim: The objective of the study was to develop and optimized bilayered sustained release floating tablet of metoprolol tartrate.
    Method: A 23 full factorial design was used with 3 factors hydroxypropyl methylcellulose K100M(X1), sodium bicarbonate(X2) and crospovidone(X3). The formulation were evaluated with 7 response variables % release in

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Last update 4 October 2019

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