Gene transfer system into human placental cells by fiber-modified adenovirus vectors
- At: 2005 FIP Congress in Cairo (Egypt)
- Type: Poster
- By: WATANABE, Yoshiteru (Showa Pharmaceutical University, Pharmaceutics and Biopharmaceutics, Tokyo, Japan)
- Co-author(s): Koizumi (Showa Pharmaceutical University, TOKYO, Japan)
Kondoh (Showa Pharmaceutical University, TOKYO, Japan)
Fujii (Showa Pharmaceutical University, TOKYO, Japan)
Mizuguchi (National Institute of Health Sciences, OSAKA, Japan)
Hayakawa (National Institute of Health Sciences, TOKYO, Japan)
Nakanishi, Tsuyoshi (Osaka University, OSAKA, Japan)
Tanaka, Keiichi (Osaka University, OSAKA, Japan)
[Purpose] Aim of this study was evaluate the ability of fiber-modified adenovirus (Ad) vectors, which can be effective in cells lacking the coxsackievirus and adenovirus receptor (CAR), to transduce human trophoblast cell lines used as in vitro models of human placenta.
[Methods] Human trophoblast cell lines, JEG-3, JAR and BeWo cells were.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.