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Pluronic f 127-based thermoreversible and mucoadhesive hydrogel for oral delivery of naproxen

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Presentations + Posters
  • By: PARK, Jeong-Sook (Chungnam National University College of Pharmacy, Daejeon, South-Korea)
  • Co-author(s): Shin, Baek-Ki (Chungnam National University College of Pharmacy, DAEJEON, South-Korea)
    Davaa, Enkhzaya (Chungnam National University College of Pharmacy, DAEJEON, South-Korea)
    Jeong, Ui-Hyeon (Chungnam National University College of Pharmacy, DAEJEON, South-Korea)
    Choi, Soon Gil (Chungnam National University College of Pharmacy, DAEJEON, South-Korea)
  • Abstract:

    The purpose of the present study was to develop oral mucosal delivery systems of naproxen using thermoreversible polymer Pluronic F127 (PF127) and mucoadhesive polymer carbopol 934P (C934P). PF127 was mixed with PBS to a concentration of 20% (w/w) and left overnight in a refrigerator at 4 °C. Sol-gel transition temperature of hydrogels was

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Last update 4 October 2019

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