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Practical problems in routine determination of molecular weight distribution in medicinal polymers and one possible solution.

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: DIDUKH, Iryna (Central Laboratory on Quality Control of Medicines and Medical Products, Kiev, Ukraine)
  • Co-author(s): Syrotchuk, Alexander (Central Laboratory on Quality Control of Medicines and Medical Products, KIEV, Ukraine)
    Zaitsev, Vladimir (Shevchenko National University, Chemical Department, KIEV, Ukraine)
  • Abstract:

    Compendial methods for molecular weight distribution (MWD) of dextrans are based on double standard approach. Narrow standards are used for calibration and broad standard should be used for system suitability test. Prescribed limits of system suitability are broad and therefore may cause large uncertainty of results. And results strongly depend on ..

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Last update 4 October 2019

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