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A genetic variant in CYP3A4 gene is associated with increased risk of coronary heart disease in Han Chinese

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: HE, Baoxia (Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, China)
  • Co-author(s): Shi, Lei (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
    Qiu, Jian (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
    Tao, Liang (Sun Yat-sen University, GUANGZHOU, China)
    Li, Rui (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
    Yang, Liang (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
    Zhao, Shujin (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  • Abstract:

    Background: There are accumulating evidences that cytochrome P450 (CYP) enzymes play crucial roles in cardiovascular disease. CYP3A4 is a major member of the CYP enzymes. Most recently, a novel mutation in the CYP3A4 gene, named CYP3A4*1G (rs2242480), has been identified, and in found to be associated with the activity of CYP3A4 enzyme. The aim of

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Last update 4 October 2019

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