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Difference on physicochemical properties and dna compaction efficiency of nanoemulsions for gene therapy using distinct surfactants

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: MAFRA VERISSIMO, Lourena (Universidade Federal do Rio Grande do Norte, Natal, Brazil)
  • Co-author(s): Alexandrino Júnior, Francisco (Universidade Federal do Rio Grande do Norte, NATAL, Brazil)
    Da Silva Martins, Alexandre (Universidade Federal do Rio Grande do Norte, NATAL, Brazil)
    Silva, André Leandro (Universidade Federal do Rio Grande do Norte, NATAL, Brazil)
    Fassarela Agnez Lima, Lucymara (Universidade Federal do Rio Grande do Norte, NATAL, Brazil)
    Tabosa Do Egito, Eryvaldo Sócrates (Universidade Federal do Rio Grande do Norte, NATAL, Brazil)
  • Abstract:

    Cationic lipid-based emulsions (CLEs) have been investigated as an alternative for non-viral gene carrier in therapeutic gene delivery due to the disadvantages related to the use of viral vectors. The aim of this work was to evaluate the influence of two different cationic lipids, 1,2-Dioleoyl-3-Trimethylammonium-Propane (DOTAP) and stearylamine, ..

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Last update 4 October 2019

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