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Development of tacrolimus sustained-release tablet prepared by solid dispersion system

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
  • Co-author(s): Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yeo, Woohyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yi, Jeong-Hun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Hwang, Doohyung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Cho, Jung Hyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yang, Kwanyeol (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Oh, Dong Hoon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  • Abstract:

    The purpose of this study is to develop a sustained-release tablet with similar dissolution profile and bioavailability to that of the commercial tacrolimus sustained-release capsule. Tacrolimus-loaded solid dispersion with enhanced solubility was prepared by spray-drying method and their physicochemical properties were investigated. Among the..

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Last update 4 October 2019

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