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In silico based structural features study of ccr5 antagonists as antihiv-1 agents

  • At: Lisbon (Portugal) (2010)
  • Type: Poster
  • By: MOORTHY, N.S. Hari Narayana (University of Porto, Porto, Portugal)
  • Co-author(s): Maria J., Ramos (University of Porto, PORTO, Portugal)
    Pedro a., Fernandes (University of Porto, PORTO, Portugal)
  • Abstract:

    HIV-1 attachment is mediated by the interaction of the viral envelope glycoprotein gp120. The interaction of transmembrane CCR5 with viral gp120 is critical for membrane fusion and virus entry; because a blockade of such binding can inhibit HIV-1 infection efficiently. In the present investigation, the antiHIV drug discovery group in our..

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Last update 4 October 2019

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