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Evaluation of penetration enhancement effect of terpenes on a highly lipophilic compound with attenuated total reflectance-fourier transform infrared (atr-ftir) spectroscopy

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: ERDAL, M Sedef (Istanbul University, Faculty of Pharmacy, Dept.of Pharmaceutical Technology, Istanbul, Turkey)
  • Co-author(s): Güngör, Sevgi (Istanbul University, Faculty of Pharmacy, Dept.of Pharmaceutical Technology, ISTANBUL, Turkey)
    Özsoy, Yildiz (Istanbul University, Faculty of Pharmacy, Dept.of Pharmaceutical Technology, ISTANBUL, Turkey)
  • Abstract:

    The purpose of this work was to investigate the effect of various terpenes in presence of two different co-solvents on topical delivery of a highly lipophilic compound (log P=5.4), naftifine HCl (NFT), in vitro.

    The clinical efficacy of topical formulations depends on the release of drug from vehicles and then, its penetration across stratum..

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Last update 4 October 2019

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