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Inhibitory activity of benzo[a]dihydrocarbazoles against human and parasite topoisomerases by means of PCR and mass spectrometry techniques

  • At: Istanbul (Turkey) (2009)
  • Type: Poster
  • By: MARTIARENA, Jorge (University of Belgrano, Buenos Aires, Argentina)
  • Co-author(s): Cobice, Diego (University of Belgrano, Buenos Aires, Argentina)
    Villamil, Silvia (University of Belgrano, Buenos Aires, Argentina)
  • Abstract:

    The benzo[a]dihydrocarbazoles synthetized by Pappa et al showed low antiparasite activity against T. Cruzi.(1). At that time there were not any described studies about the biological mechanism. Starting from these results we carried out theoretical studies of chemical properties about the drugs mentioned above and doxorubicin, in order to improve


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Last update 4 October 2019

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