Salbutamol sulfate in-situ nasal gelling systems: formulation and evaluation
- At: 2009 FIP Congress in Istanbul (Turkey)
- Type: Poster
- By: NADA, Aly (Faculty of Pharmacy, Kuwait, Kuwait)
- Co-author(s): Etman, Mohamed (Faculty of Pharmacy, ALEXANDRIA, Egypt)
Farid, Ragwa (Faculty of Pharmacy, ALEXANDRIA, Egypt)
Ebian, Abd-Elazim (Faculty of Pharmacy, ALEXANDRIA, Egypt)
Nada, Aly (Faculty of Pharmacy, KUWAIT, Kuwait)
Introduction: Oral or swallowed portion of inhaled salbutamol undergoes first-pass metabolism. Nasal delivery is supposed to protect drugs from hepatic first-pass metabolism. Mucoadhesive in-situ gels for salbutamol sulfate (SS) with gellan gum were formulated and tested in rats.
Methods: SS in-situ gels (2% w/w) were prepared in deionized water.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.