Salbutamol sulfate in-situ nasal gelling systems: formulation and evaluation

• In: Industrial Pharmacy- Posters
• At: Istanbul (Turkey) (2009)
• Type: Poster
• Poster code: IPS-P-014
• By: NADA, Aly (Faculty of Pharmacy, Kuwait, Kuwait)
• Co-author(s): Etman, Mohamed (Faculty of Pharmacy, ALEXANDRIA, Egypt)
  Farid, Ragwa (Faculty of Pharmacy, ALEXANDRIA, Egypt)
  Ebian, Abd-Elazim (Faculty of Pharmacy, ALEXANDRIA, Egypt)
  Nada, Aly (Faculty of Pharmacy, KUWAIT, Kuwait)
  
• Abstract:

  Introduction: Oral or swallowed portion of inhaled salbutamol undergoes first-pass metabolism. Nasal delivery is supposed to protect drugs from hepatic first-pass metabolism. Mucoadhesive in-situ gels for salbutamol sulfate (SS) with gellan gum were formulated and tested in rats.
  
  Methods: SS in-situ gels (2% w/w) were prepared in deionized water..

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