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Effect of curcumin prodrug fm0806 on mouse hepatic carcinoma h22 in vivo

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: XU, Jianhua (Fujian Medical University, Fuzhou, China)
  • Co-author(s): Lin, Yanfang (Fujian Medical University, FUZHOU, China)
    Liu, Yang (Fujian Medical University, FUZHOU, China)
    Huang, Xiuwang (Fujian Medical University, FUZHOU, China)
    Wu, Lixian (Fujian Medical University, FUZHOU, China)
  • Abstract:

    Curcumine(Cur) a potent anticancer agent however, is not a viable candidate drug due to its poor bioavailability.To improve the bioavailability, we have designed and synthesized a novel Cur prodrug FM0806.It showed no spontaneous hydrolysis at pH 7.4, but was susceptible to hydrolysis and release Cur by homogenized liver and blood..

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Last update 4 October 2019

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