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Xanthohumol, a prenylated flavonoid present in the hop plant (humulus lupulus), and its synthetic derivatives inhibit angiogenesis and tumor invasion

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, South-Korea)
  • Co-author(s): Kang, You-Ra (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Jong Suk (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Park, Su-Young (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Choi, Mi Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Yong Rok (School of Chemical Engineering and Technology, Yeungnam University, South-Korea)
    Noh, Seok Kyun (School of Chemical Engineering and Technology, Yeungnam University, South-Korea)
    Park, Jyung Rewng (Department of Food and Nutrition, Yeungnam University, South-Korea)
    Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  • Abstract:

    Angiogenesis is an invasive process that is also important for the tumor cell invasion and metastasis. Previously, xanthohumol has been shown chemopreventive and anti-angiogenic activities. In this study, we have examined the anti-angiogenic and anti-invasive activities of xanthohumol and its synthetic derivatives L5, L6, and L7. The inhibitory..

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Last update 4 October 2019

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