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Effects of oridonin on hepatic cytochrome p450 expression and activities in pxr-humanized mice
- At: Glasgow (Scotland) (2018)
- Type: Poster
- Poster code: POS-NPR-026
- By: ZHANG, Yiwen (Zhejiang Cancer Hospital)
- Co-author(s): Yiwen Zhang: Laboratory of Clinical Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
Mei-Hua Bao: Department of Anatomy, Histology and Embryology, Changsha Medical University, Changsha, China
Like Zhong: Laboratory of Clinical Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
Ping Huang: Laboratory of Clinical Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China - Abstract:
Background
Oridonin, the major terpene found in Rabdosia rubescens, is widely used as dietary supplement or therapeutic drug, while the effects of oridonin on CYP450 were still unclear [1]. The pregnane X receptor (PXR) is an important regulatory factor for major drug metabolism enzyme cytochrome P450 (CYPs), and it has been reported to.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023