Molecularly targeted dual drug loaded lipid-protein hybrid nanoparticles for synergistic combinational chemotherapy

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Jae Hee Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Hima Bindu Ruttala: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Gyeong Jin An: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Myung-Ja Hong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jee-Heon Jeong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han-Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Background

    Abraxane® showed some potential limitations including hypersensitivity reactions importantly its poor colloidal stability, which results in a poor pharmacokinetic pattern in the systemic circulation.

    Purpose

    A transferrin-anchored albumin nanoplatform with PEGylated lipid bilayers(Tf-L-APVN) was developed for the targeted co-delivery of..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login