The impact of ethanol content and neutralizer selection on the rheology and stability of hydroalcoholic carbomer gels for topical drug delivery
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: TAN, Bernice Mei Jin (ANGUS Chemical Company, ANGUS Life Sciences, Singapore, Singapore)
- Co-author(s): Bernice Mei Jin Tan: ANGUS Life Sciences, ANGUS Chemical Company, Singapore, Singapore
Carbomers are cross-linked polyacrylic acid polymers used as gelling agents in topical drug products. Gel formation occurs in two stages: (i) dispersion and hydration and (ii) neutralization of -COOH groups by a basic compound. In order to solubilize lipophilic drugs, non-polar solvents like ethanol are added to gels. The compatibility.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.