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Determination of liquid amount in batch and continuous wet granulation using mixer torque rheometry

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KYTTä, Kaisa (Punkalaidun, Finland)
  • Co-author(s): Kaisa Kyttä: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Satu Lakio: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
    Håkan Wikström: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
    Magnus Fransson: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
    Gunnar Haeffler: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
    Jarkko Ketolainen: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
    Jonas Ödman: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
    Pirjo Tajarobi: Pharmaceutical Technology and Development, AstraZeneca, Gothenburg, Sweden
  • Abstract:

    Backgrounds


    Wet granulation is a commonly used unit operation in pharmaceutical manufacturing of oral solid dosage forms, yet the choice of liquid amount for granulation is often done by trial and error.

    Aims

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Last update 4 October 2019

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