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Physicochemical and dissolution properties of ibuprofen-DEAE-Dextran nanoconjugates prepared by hydrotropic solubilization

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KOLA-MUSTAPHA, Adeola (University of Ilorin, Ilorin Nigeria, Ifako-Ijaye, Nigeria)
  • Co-author(s): Adeola Tawakalitu Kola-Mustapha: Pharmaceutics and Industrial Pharmacy, University of Ilorin, Ilorin, Nigeria
    Amos Olusegun Abioye: School of Pharmacy, De Montfort University, Leicester, United Kingdom
  • Abstract:


    Ibuprofen, a BCS class II drug requires a high loading dose to be effective. In this study, the possibility of combining polyelectrolytes with hydrotropes was explored to form secondary complexes with effects on release profiles and stability of novel nanoconjugates.  


    To enhance the solubility of ibuprofen by the combined advantage


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Last update 4 October 2019

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