Menu
  • Join
  • Login
  • Contact
 

Search abstracts


Quantitative evaluation of absorption and metabolism of p-aminobenzoic acid in rat intestine

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: OHURA, Kayoko (Kumamoto University, Priority Organization for Innovation and Excellence, Kumamoto, Japan)
  • Co-author(s): Kayoko Ohura: Priority Organization for Innovation and Excellence, Kumamoto University, Kumamoto, Japan
    Keiichiro Tanaka: Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Takahiro Yonemitsu: Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Teruko Imai: Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
  • Abstract:

    Backgrounds

    p-Aminobenzoic acid (PABA) has been long used as an indicator to assess the completeness of 24 hour urine collections. The urinary recovery of PABA is above 85% after orally dosing. However, PABA is a substrate of arylamine N-acetyltransferase expressed in both human and rat intestine. The intestinal metabolism of PABA to N-acetyl-PABA..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses