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Dual release and in vivo evaluation in beagle dogs of bilayer matrix tablet containing aceclofenac

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: LEE, Beom-Jin (Ajou University, College of Pharmacy, Suwon, Korea, Republic Of)
  • Co-author(s): Beom-Jin Lee: College of Pharmacy, Ajou University, Suwon, Korea, Republic Of
    Won-Ho Kang: College of Pharmacy, Ajou University, Suwon, Korea, Republic Of
    Hien Nguyen: College of Pharmacy, Ajou University, Suwon, Korea, Republic Of
    Chulhun Park: College of Pharmacy, Ajou University, Suwon, Korea, Republic Of
    Dong Hwan Sohn: College of Pharmacy, Keimyung University, Daegu, Korea, Republic Of
    Hyo-Kyung Han: College of Pharmacy, Dongguk, Ilsan, Korea, Republic Of
  • Abstract:

    Backgrounds

    Aceclofenac (AFC), a non-steroidal anti-inflammatory drug (NSAID), is known to show poor dissolution, insufficient oral bioavailability and gastroduodenal mucosal lesions. 

    Aims

    The aims of this study were to develop a once-daily AFC bilayer matrix tablet (AFC-CR), releasing drug immediately and in a controlled fashion. The role of an

    ..

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Last update 4 October 2019

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