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PEGylated liposomes for topical vaginal therapy: Improved delivery of interferon alpha

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: SKALKO-BASNET, Natasa (University of Tromso, Pharmacy, Tromso, Norway)
  • Co-author(s): May Wenche Jøraholmen: Department of Pharmacy, University of Tromsø, Tromsø, Norway
    Purusotam Basnet: Department of Obstetrics and Gynecology, University Hospital of North Norway, Tromsø, Norway
    Ganesh Acharya: Department of Clinical Science, Intervention & Technology, Karolinska Institute, Stockholm, Sweden
    Natasa Skalko-Basnet: Department of Pharmacy, University of Tromsø, Tromsø, Norway
  • Abstract:

    Backgrounds

    Local therapy based on biologicals remains a challenge, especially in vaginal therapy. Recent studies indicate that nanosystems with surface-available polyethylene glycol (PEG) are able to penetrate mucus barrier, assure closer contact with the epithelium, and improve drug delivery to vagina.

    Aims

    In the present work, we aimed to develop

    ..

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Last update 4 October 2019

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