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In vitro CACO-2 cell permeability studies of ritonavir nanosuspension formulation

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: CELEBI, Nevin (Gazi University Faculty of Pharmacy, Pharmaceutical Technology, Ankara, Turkey)
  • Co-author(s): Alptug Karakucuk: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
    Naile Ozturk: Pharmaceutical Technology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
    Imran Vural: Pharmaceutical Technology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
    Zeynep Safak Teksin: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
    Nevin Celebi: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
  • Abstract:

    Backgrounds

    Nanosupensions provide benefits to improve saturation solubility, dissolution and permeability of drugs related to their nanosized particles.

    Aims

    The objective of this study was to evaluate cytotoxic effect and permeability of ritonavir nanosuspension on Caco-2 cells in comparison with coarse ritonavir powder and physical mixtures. 

    Method

    ..

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Last update 4 October 2019

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