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High intracellular cholesterol level reduces the sensitivity to EGFR-TKI therapy may via ATP-binding cassette transporters in non-small cell lung cancer harboring EGFR mutations

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: CHEN, Qiufang (China Pharmaceutical University, Nanjing, China)
  • Co-author(s): Qiufang Chen: China Pharmaceutical University, Nanjing, China
    Chen Qiao: China Pharmaceutical University, Nanjing, China
    Wenjuan Ye: China Pharmaceutical University, Nanjing, China
    Xiaomei Wu: China Pharmaceutical University, Nanjing, China
    Xuansheng Ding: China Pharmaceutical University, Nanjing, China
    Liyun Miao: The affiliated Drum Tower Hospital of Nanjing University Medical College, Nanjing, China
  • Abstract:

    Backgrounds

    Cancer cells need excess cholesterol to maintain a high level of proliferation is well accepted, however whether intracellular cholesterol level associates with epidermal growth factor receptor-tyrosine kinase inhibitors resistance in non-small cell lung cancer harboring EGFR mutations has not been elucidated. 

    Aims

    To explore

    ..

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Last update 4 October 2019

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