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Asiatic Acid Enhances Intra-tumoral Accumulation and Antitumor Effect of Pegylated Liposomal Doxorubicin by Remodeling Tumor Stroma

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: FANG, Luo (Zhejiang Cancer Hospital, Department of Pharmacy, Hangzhou, China)
  • Co-author(s): Luo Fang: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Like Zhong: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Yiwen zhang: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Haiying Ding: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Wenxiu Xin: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Yinhui Tong: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
    Ping Huang: Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China
  • Abstract:

    Backgrounds

    The microenvironment of tumor is critical in the genesis and progression of tumor. Most recently, it was disclosed that desmoplastic stroma causing by collagen deposition could lead to therapy resistance by limiting the intratumoral convection, diffusion and accumulation of antineoplastic agents. Therefore, therapeutic intervention by..

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Last update 4 October 2019

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