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A comparison of performance between parametric and nonparametric estimation for nonlinear mixed-effects models

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: WANG, Shijun (Uppsala University, Department of pharmaceutical bioscience, uppsala, Sweden)
  • Co-author(s): Shijun Wang: Department of pharmaceutical bioscience, Uppsala University, uppsala, Sweden
    Andrew Hooker: Department of pharmaceutical, Uppsala University, Uppsala, Sweden
    Mats Karlsson: Department of pharmaceutical bioscience, Uppsala University, Uppsala, Sweden
  • Abstract:


    Nonparametric (NP) methods estimating discrete parameter distributions offer an alternative to parametric methods in pharmacometric analyses.


    This study aims to evaluate the performance of the NP estimation method in NONMEM 7 in comparison with the first-order conditional estimation method with interaction (FOCEI)1


    The FOCEI


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Last update 4 October 2019

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