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An effective online method for assessing the absolute enantiomeric excess and conversion ratio of asymmetric reactions

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: ZHANG, Xiang (Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing Key Laboratory of Active Substances, Discovery and Druggability Evaluation, Beijing, China)
  • Co-author(s): Xiang Zhang: Beijing Key Laboratory of Active Substances, Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China
    Mingchao Wang: Beijing Key Laboratory of Active Substances, Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China
    Li Li: Beijing Key Laboratory of Active Substances, Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China
    Dali Yin: State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China
  • Abstract:

    Backgrounds

    Asymmetric reactions often need to be evaluated during the synthesis of chiral compounds. However, traditional evaluation methods require the isolation of the individual enantiomer, which is tedious and time-consuming.

    Aims

    It is desirable to develop a simple, practical online detection method for assessing the asymmetric reactions .

    Method

    ..

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Last update 4 October 2019

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