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Discovery and identification of Hsp90-Cdc37 PPI modulators through multiple drug discovery strategies

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: WANG, Lei (China Pharmaceutical University, Department of Medicinal Chemistry, NANJING, China)
  • Co-author(s): Lei Wang: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
    Ruoning Wang: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
    Qidong You: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
  • Abstract:

    Backgrounds

    Targeting Hsp90-Cdc37 PPI is becoming an alternative approach for future anti-cancer drug development. However, up to now, there is no small molecule reported which make this target an interesting and challenging one for drug discovery.

    Aims

    Finding Hsp90-Cdc37 PPI modulators with high affinity and selectivity as an alternative strategy

    ..

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Last update 4 October 2019

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