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New molecules against colistin-resistant clinical Acinetobacter baumannii strains. Synthesis of a small library of piperazine thiourea derivatives and in vitro biological evaluation.

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: VEGA-PéREZ, José M. (Universidad de Sevilla. Facultad de Farmacia, Dpto. Química Orgánica y Farmacéutica, Sevilla, Spain)
  • Co-author(s): Sarah Mazzotta: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
    Margarita Vega-Holm: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
    Fernando Iglesias-Guerra: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
    Javier Sánchez-Céspedes: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
    Jerónimo Pachón: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
    Mª Eugenia Pachón-Ibáñez: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
    José M. Vega-Pérez: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
  • Abstract:

    Backgrounds

    The development of active compounds against Acinetobacter baumannii is an important goal of research, due to the number of nosocomial infections it causes and to its multidrug antimicrobial resistance.


    Based on our previous work in the synthesis of small libraries of biologically active compounds, after a preliminary screening, a 


    ..

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Last update 4 October 2019

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