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Pharmacokinetics and preventive effects of platinum nanoparticles as reactive oxygen species scavengers on hepatic metastasis

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: KATSUMI, Hidemasa (Kyoto Pharmaceutical University, Biopharmaceutis, Kyoto, Japan)
  • Co-author(s): Hidemasa Katsumi: Biopharmaceutis, Kyoto Pharmaceutical University, Kyoto, Japan
    Shoko Maruyama: Biopharmaceutis, Kyoto Pharmaceutical University, Kyoto, Japan
    Kosuke Kusamori: Biopharmaceutis, Kyoto Pharmaceutical University, Kyoto, Japan
    Sakane Toshiyasu: Biopharmaceutis, Kyoto Pharmaceutical University, Kyoto, Japan;Pharmaceutical Technology, Kobe Pharmaceutical University, Kobe, Japan
    Akira Yamamoto: Biopharmaceutis, Kyoto Pharmaceutical University, Kyoto, Japan
  • Abstract:

    Backgrounds

    Oxidative stress is recognized as being involved in the pathogenesis of hepatic metastasis. Therefore, reactive oxygen species (ROS) scavengers have been considered as therapeutic agents for hepatic metastasis. We have recently developed citric acid-protected platinum nanoparticles (Pt-NPs) with ROS-scavenging properties for the

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Last update 4 October 2019

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