The science and the development of no-addictive opioid receptor agonists
- At: 2016 FIP Congress in Buenos Aires (Argentina)
- Type: Presentation
- By: NAGASE, Hiroshi (University of Tsukuba, WPI-IIIS, Nagase Laboratory, Tsukuba, Japan)
- Co-author(s): Hiroshi Nagase:
For the past three decades, considerable efforts have focused on the search for an opioid κappa-receptor ,selective agonist without the undesirable morphine-like side effects (e.g., respiratory depression, constipation, physical dependence, etc.). In 1982, U-50488H was discovered to be a highly selective κappa-agonist. Subsequently, most of the.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.