Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia
- At: 2016 FIP Congress in Buenos Aires (Argentina)
- Type: Poster
- By: SUN, Lulu (BEIJING SHIJITAN HOSPITAL, Beijing, China)
- Co-author(s): Lulu Sun:
acute lymphoblastic leukemia, methotrexate, folylpolyglutamate synthase, gamma-glutamyl hydrolase, methylenetetrahydrofolate reductase, single nucleotide polymorphisms.
Ninety-one children with ALL who received high-dose MTX were recruited. The polymorphisms FPGS (rs1544105 G>A), GGH (rs3758149 C>T), and MTHFR (rs1801133 C>T) were genotyped through.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.