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Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia

  • At: 2016 FIP Congress in Buenos Aires (Argentina)
  • Type: Poster
  • By: SUN, Lulu (BEIJING SHIJITAN HOSPITAL, Beijing, China)
  • Co-author(s): Lulu Sun:
  • Abstract:

    acute lymphoblastic leukemia, methotrexate, folylpolyglutamate synthase, gamma-glutamyl hydrolase, methylenetetrahydrofolate reductase, single nucleotide polymorphisms.

    Ninety-one children with ALL who received high-dose MTX were recruited. The polymorphisms FPGS (rs1544105 G>A), GGH (rs3758149 C>T), and MTHFR (rs1801133 C>T) were genotyped through

    ..

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Last update 4 October 2019

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