Synthesis, structure , antitumor activity and mechanism of a new diorganotin ( iv ) complex with arylhydroxamate [ (n-bu)2sn(c7h5o2ncl)cl ]
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: LI, Yunlan (Shanxi Medical University, Shanxi, China)
- Co-author(s): YANG, Li (Shanxi Medical University, SHANXI, China)
NIU, Xiao-Qiang (Shanxi Medical University, SHANXI, China)
LIANG, Tai-Gang (Shanxi Medical University, SHANXI, China)
OBJECTIVE: To synthetize a new diorganotin ( IV ) complex and study its antitumor activities in vivo and in vitro and action mechanism . METHODS: Reaction of di-n-butyltin ( IV ) dichloride with 4-chlorobenzohydroxamic acid yielded a new mixed-ligand diorganotin ( IV ) complex. Use Kunming mice as transplantable carcinomas animal models. The.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.