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Identification of novel human high-density lipoprotein receptor up-regulators using a cell-based high throughput screening assay

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: HONG, Bin (Institute of Medicinal Biotechnology, Beijing, China)
  • Co-author(s): Yang, Yuan (Institute of Medicinal Biotechnology, BEIJING, China)
    Zhang, Zhongbing (Institute of Medicinal Biotechnology, BEIJING, China)
    Jiang, Wei (Institute of Medicinal Biotechnology, BEIJING, China)
    Gao, Lei (Institute of Medicinal Biotechnology, BEIJING, China)
    Zhao, Guiyu (Institute of Medicinal Biotechnology, BEIJING, China)
    Zheng, Zhihui (Institute of Medicinal Biotechnology, BEIJING, China)
    Si, Shuyi (Institute of Medicinal Biotechnology, BEIJING, China)
  • Abstract:

    Scavenger receptor class B type I (SR-BI) is the high-affinity HDL receptor, and the CLA-1 is the human homologue of the murine SR-BI. CLA-1/SR-BI receptor has been suggested as a new preventative and/or therapeutic target for atherosclerosis due to its pivotal role in overall HDL cholesterol (HDL-C) metabolism and its anti-atherogenic activity in ..

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Last update 13 May 2019

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