IMPACT OF SCN1A, ABCB1 AND EPHX1 POLYMORPHIC VARIANTS IN PLASMA CARBAMAZEPINE CONCENTRATIONS AND PHARMACORESISTANCE IN KOSOVAR POPULATION
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Presentation
- By: DACI, Armond (Faculty of Medicine, Pharmacy, Prishtina, Kosovo)
- Co-author(s): Armond Daci
The pharmacokinetics and pharmacodynamics of carbamazepine (CBZ) vary widely among patients withepilepsy.
For 145 epileptic patients treated with CBZ as monotherapy and 100 healthy control, five SNPs in candidate genes ABCB1, EPHX1, and SCN1A were analyzed by genotyped using Real Time PCR was run using SNP Specific Predesigned Taqman Probes... The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.