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DRUG –DRUG INTERACTIONS BETWEEN RILPIVIRINE AND ABACAVIR ON ABC TRANSPORTERS

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: CECKOVA, Martina (Charles University Prague, Faculty of Pharmacy, Dpt. of Pharmacology and Toxicology, Hradec Kralove, Czech Republic)
  • Co-author(s): Martina Ceckova
  • Abstract:

    Rilpivirine is a non-nucleoside reverse transcriptase inhibitor approved for the combination antiretroviral therapy of HIV infection. As many antiretroviral drugs are substrates or inhibitors of ATP-dependent (ABC) drug efflux transporters, their combinations bear a risk of drug-drug interactions (DDI).

    We investigated inhibitory potency of

    ..

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Last update 4 October 2019

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