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TUMOR NECROSIS FACTOR Α-INDUCED
INTESTINAL INFLAMMATION WAS SUPPRESSED BY ISOLIQUIRITIGENIN VIA REGULATING HMGB1 RELEASE

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: SOHN, Dong Hwan (Wonkwang University, Pharmacy, Iksan, South-Korea)
  • Co-author(s): Dong , Hwan Sohn
  • Abstract:

    High mobility group box 1 (HMGB1) is a non-histone nuclear protein. It will be secreted from activated cells and then recognized as a pro-inflammatory cytokine in various diseases including inflammatory bowel disease (IBD). Isoliquiritigenin(ISQ), a flavonoid from licorice, has anti-inflammatory potent in inflammatory disease.

    The protein

    ..

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Last update 4 October 2019

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