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FORMULATION AND EVALUATION OF FAST DISSOLVING ORAL FILMS CONTAINING LERCANIDIPINE NANOCRYSTALS

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: CHONKAR, Ankita (Manipal College of Pharmaceutical Sciences, Manipal, India)
  • Co-author(s): Nayanabhirama Udupa
  • Abstract:

    Lercanidipine (LR) is dihydropyridine calcium antagonist, mainly used for the treatment of hypertension and angina pectoris. However, it suffers from food dependant absorption, poor solubilty, low permeability and considerable first pass metabolism, resulting in highly variable and low bioavailability of 10%.

    Nanocrystals of lercanidipine were

    ..

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Last update 4 October 2019

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