DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL SPIROISOXAZOLIN DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: ABOLHASANI, Hoda (School of Medicine, Qom University of Medical Sciences, Qom, Iran, Departement of Pharmacology, Qom, Iran)
- Co-author(s): Hoda Abolhasani
Chronic inflammation may be a causative factor in a variety of cancers. Selective COX-2 inhibitors are used as anti-inflammatory agents and COX-2 over expression has been demonstrated in several cancers.
New spiroisoxazoline derivatives were designed and synthesized for evaluation as selective COX-2 inhibitors by Cayman kit. Docking studies were.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.