DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL SPIROISOXAZOLIN DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
- In: Poster Session
- At: Düsseldorf (Germany) (2015)
- Type: Poster
- By: ABOLHASANI, Hoda (School of Medicine, Qom University of Medical Sciences, Qom, Iran, Departement of Pharmacology, Qom, Iran)
- Co-author(s): Hoda Abolhasani
Chronic inflammation may be a causative factor in a variety of cancers. Selective COX-2 inhibitors are used as anti-inflammatory agents and COX-2 over expression has been demonstrated in several cancers.
New spiroisoxazoline derivatives were designed and synthesized for evaluation as selective COX-2 inhibitors by Cayman kit. Docking studies were.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.