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BISPECIFIC T-CELL ENGAGING ANTIBODIES FOR CANCER THERAPY

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Presentation
  • By: WOLF, Andreas (Amgen Research Munich, München, Germany)
  • Co-author(s): Andreas Wolf
  • Abstract:

    BiTE™ antibodies are single-chain bispecific antibody constructs with specificity for CD3 on T cells and a selected surface antigen on target cells. By transiently bridging T cells and cancer cells, BiTE™ antibodies are capable to fully activate T cells and to mount a polyclonal T cell response that is no longer restricted by T cell receptor

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Last update 4 October 2019

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