Dsc and ft-ir as tools to evaluate drug-polymer interactions in microparticulate systems
- At: 2006 FIP Congress in Salvadore (Brazil)
- Type: Poster
- By: LIRA, Ana Amélia (FCFRP/USP, RibeirÃo Preto, Brazil)
- Co-author(s): Marchetti, Juliana (FCFRP/USP, RIBEIRÃO PRETO, Brazil)
Nanclares, Denise (FCFRP/USP, RIBEIRÃO PRETO, Brazil)
Federman Neto, Alberto (FCFRP/USP, RIBEIRÃO PRETO, Brazil)
Chitosan microparticles were prepared with the purpose of incorporating all-trans retinoic acid (ATRA). Morphology, drug content and the release behavior of microparticles were assessed. The interaction between chitosan and ATRA (acidic drug) using differential scanning calorimetry (DSC) and infrared (IR) spectroscopy as the relation of such.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.