Construction and application of biotin–poloxamer conjugate micelles for chemotherapeutics
- At: 2014 FIP Congress in Bangkok (Thailand)
- Type: Poster
- By: LIN, Guang-Yong (The Second Affiliated Hospital of Wenzhou Medical College, department of Pharmacy, Wen zhou, China)
ABSTRACT: OBJECTIVE Biotin was conjugated on poloxamer to prepare biotin-poloxamer (BP) conjugate micelles for chemother-apeutics. METHODS Epirubicin (EPI) was encapsulated in BP micelles. The EPI-loaded BP micelles were characterized in terms of size, -potential, morphology, drug loading, drug encapsulation and drug release. Marrow leuke-mic.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.