The in vitro profile assessment of fluticasone propionate and cyclodextrins binary systems
- At: 2014 FIP Congress in Bangkok (Thailand)
- Type: Poster
- By: Sá COUTO, André (Faculty of Pharmacy University of Lisbon, Pharmaceutical Technology, Lisbon, Portugal)
- Co-author(s): Monod, Stephanie (Faculty of Pharmacy University of Lisbon, Lisbon, Portugal)
Cabral-Marques, Helena (Faculty of Pharmacy University of Lisbon, Lisbon, Portugal)
I.Background information:To overcome the limitation of corticosteroids formulations (namely high lipophilicity), its association with cyclodextrins (CyDs) has been used to improve the water solubility and to reduce the dose required to get a local effect at lungs, thus reducing their side effects.
CyDs are non-toxic excipients with a lipophylic.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.