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Radiochemical determination of catechol-o-methyltransferase activity in blood vessels of diabetic rats.

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: CARAMONA, Margarida (Coimbra University, Coimbra, Portugal)
  • Co-author(s): Marques (Faculdade de Farmácia - Coimbra, COIMBRA, Portugal)
    Nunes, Sandra Fernanda (Coimbra University, COIMBRA, Portugal)
    Costa (Coimbra University, COIMBRA, Portugal)
    Morgadinho (Pharmacology Institute, COIMBRA, Portugal)
    Figueiredo (Coimbra University, COIMBRA, Portugal)
  • Abstract:

    Catechol–O–methyltransferase (COMT) is the enzyme responsible for the O-methylation of catecholamines widely distributed in tissues from various mammalian species and with high levels of activity. The hypothesis that the COMT is related to diabetes is based on evidence that there are some changes in catecholamine metabolism in patients who..

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Last update 4 October 2019

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