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Cellular models and clinical relevance of renal transporter-mediated drug-drug interactions

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: FROMM, Martin F. (Friedrich-Alexander-University Erlangen-N, Chair, Clinical Pharmacology and Clinical Toxicology, Erlangen, Germany)
  • Abstract:

    Transporter proteins determine plasma concentrations and effects of a broad variety of drugs. They can functionally be divided into uptake transporters (e.g. organic anion transporters, OATs; organic cation transporters, OCTs) and efflux transporters (e.g. P-glycoprotein, MDR1; breast cancer resistance protein, BCRP; multidrug resistance protein

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Last update 4 October 2019

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