Cellular models and clinical relevance of renal transporter-mediated drug-drug interactions
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: FROMM, Martin F. (Friedrich-Alexander-University Erlangen-N, Chair, Clinical Pharmacology and Clinical Toxicology, Erlangen, Germany)
Transporter proteins determine plasma concentrations and effects of a broad variety of drugs. They can functionally be divided into uptake transporters (e.g. organic anion transporters, OATs; organic cation transporters, OCTs) and efflux transporters (e.g. P-glycoprotein, MDR1; breast cancer resistance protein, BCRP; multidrug resistance protein.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.