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Alteration of skin hydration and its barrier function by vehicles and permeation enhancers: a study using tga, ftir, tewl and drug permeation as markers

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: PANCHAGNULA, Ramesh (University of Ulster, Coleraine, United Kingdom)
  • Co-author(s): Shah, Dhaval Kumar (NIPER, MOHALI, India)
    Khandavilli, Sateesh (NIPER, MOHALI, India)
  • Abstract:

    The present investigation was designed to study the effect of most commonly used vehicles and PE on rat skin hydration, barrier function and permeation of an amphiphilic drug Imipramine hydrochloride (IMH). Thermo gravimetric analysis (TGA) and Fourier transform infrared (FTIR) spectroscopy were utilized to determine changes in skin hydration...

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Last update 4 October 2019

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