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Nhba exerts sedative and hypnotic effects in sodium pentobarbital-treated mice

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: ZHANG, Jianjun (Institute of Materia Medica, CAMS, Pharmacology, Beijing, China)
  • Abstract:

    The rhizomes of Gastrodia elata have been used for the treatment of insomnia in oriental countries. N6-(4-hydroxybenzyl) adenine riboside (NHBA) was originally isolated from G. elata. For the first time we report a detailed study on the effects and mechanisms of NHBA on its sedative and hypnotic activity. Adenosine, an endogenous sleep factor,..

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Last update 4 October 2019

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