Nhba exerts sedative and hypnotic effects in sodium pentobarbital-treated mice
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: ZHANG, Jianjun (Institute of Materia Medica, CAMS, Pharmacology, Beijing, China)
The rhizomes of Gastrodia elata have been used for the treatment of insomnia in oriental countries. N6-(4-hydroxybenzyl) adenine riboside (NHBA) was originally isolated from G. elata. For the first time we report a detailed study on the effects and mechanisms of NHBA on its sedative and hypnotic activity. Adenosine, an endogenous sleep factor,.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.