Development of novel flexible lipid-vesicles of an estrogen receptor modulator

• In: J8 - Competition - Short Oral Communications of the FIP Industrial Pharmacy Section on Tuesday, 6 September 2011, 14:15-16:45
• At: Hyderabad (India) (2011)
• Type: Presentations + Posters
• By: DHONE, Deepa (UIPS, Panjab University, Chandigarh, India)
• Co-author(s): Bhatia, Amit (UIPS, Panjab University, Chandigarh, India)
  Raza, Kaisar (UIPS, Panjab University, Chandigarh, India)
  Singh, Bhupinder (UIPS, Panjab University, Chandigarh, India)
  Katare, Om Prakash (UIPS, Panjab University, Chandigarh, India)
  
• Abstract:

  Tamoxifen (TAM) is a non-steroidal estrogen receptor modulator indicated in the management of breast cancer. The key objectives of the study include development, optimization, characterization and evaluation of flexible lipid-vesicles (FLVs) of TAM for in-vitro cytotoxicity and pharmacodynamic activity using suitable animal models. TAM-loaded FLVs

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