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Implementing interventions in health care – how do we MAKE-IT work?

  • At: PPR 2022 (2022)
  • Type: Poster
  • Poster code: PM-30
  • By: JANSSEN, Ruby (Hogeschool Utrecht)
  • Co-author(s): Ruby Janssen, Pharmacist, Researcher, Teacher, Hogeschool Utrecht, Netherlands
    Ellen Koster, Associate Professor
    Rob Heerdink, Lector
    Marcel Bouvy, Professor
    Liset van Dijk, Professor
    Marcia Vervloet, Senior Researcher

  • Abstract:

    Implementing interventions in health care – how do we MAKE-IT work?

    Authors: R.A. Janssen, E.S. Koster, E.R. Heerdink, M.L. Bouvy, M. Vervloet, L. van Dijk for the MAKE-IT Consortium (

    Background Over the past decades, numerous interventions have been developed to promote medication adherence in patients, but implementation in daily practice is often lacking. The MAKE-IT (Medication Adherence Knowledge Expertise and Implementation Taskforce) Consortium was set up to support Living Labs in the Netherlands in implementing established medication adherence improvement interventions in primary care settings.

    Objective The aim of this project is to assess the support to Living Labs in clinical practice in their implementation of medication adherence promoting interventions, for example by examining context and settings, studying implementation-barriers and facilitators, supporting in scaling-up the innovations to implement them widely.

    Method The Living Labs have been actively supported by the MAKE-IT consortium. Each Living Lab was guided by a team of consortium members, consisting of experienced adherence researchers and health services experts. Activities included support in developing a suitable project-idea, support in writing a protocol, workshops, evaluation of barriers and facilitators, trainings, reflection meetings, monthly support meetings, helpdesk and expert support.

    Results Four selected Living Labs in primary care have been implementing a different intervention to improve medication adherence, ever since 2020. Each Living Lab consisted of (among others) general practitioners, pharmacy technicians, nurse specialists and patients, with primary care pharmacists in the lead. The interventions promoting medication adherence were aimed at start of therapy (2 Living Labs), chronic therapy (2 Living Labs) and patients with limited health literacy. These interventions were intended for approximately 500 patients per Living Lab. Support by the MAKE-IT teams was overall appreciated, pharmacists indicated that they highly valued the reflection meetings. Implementation of the interventions in the four Living Labs has been successfully performed.

    Conclusion Four Living Labs have been running feasible projects to improve medication adherence in daily practice. Living Labs indicate the importance of support and expert opinions by the MAKE-IT Consortium during the implementation. They also state support was important for creating a sustainable change in routine practice and for scaling up the interventions and implement them widely. The next four living labs will start their projects nearby summer 2022.

Last update 4 October 2019

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