Synthesis and evaluation of anti-inflamatory activity of 2,5-diarylfuran amino acids

• In: Medicinal Chemistry Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: MC-P-006
• By: STEFANI, Hélio A. (Universidade de São Paulo, SÃo Paulo, Brazil)
• Co-author(s): Botteselle, Giancarlo V (Universidade de São Paulo, SÃO PAULO, Brazil)
  Farsky, Sandra H. P. (Universidade de São Paulo, SÃO PAULO, Brazil)
  Hebeda, Cristina B. (Universidade de São Paulo, SÃO PAULO, Brazil)
  Zukerman-Schpector, Julio (Universidade Federal de São Carlos, SÃO CARLOS, Brazil)
  
• Abstract:

  Molecules functionalized with amino or carboxyl groups are commonly used for the conjugation of biomolecules,1 and have several applications in biomedical research.
  
  Synthesis of the 2,5-diarylfuran(3-AFA)was performed as described in the literature.2 The reaction conditions for promotion of the peptide bond between the 3-AFA and the Boc-glycine..

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