A novel interferon-alpha inhibitor reduces histopathological complications in a mouse model of hiv encephalitis

• In: Posters C - Drug Design and Discovery
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PC-009
• By: SHAWAHNA, Ramzi (An-najah national university, Pharmacy, Nablus, Palestinian Territory)
• Co-author(s): Fritz-French, Cari (Emory University School of Medicine, Department of Neurology, Atlanta, United States of America)
  Tyor, William R. (Emory University School of Medicine, Department of Neurology, Atlanta, United States of America)
  
• Abstract:

  Background: HIV-associated neurocognitive disorders (HAND) are still highly prevalent in HV seropositive patients. Interferon-alpha (IFNα) has been identified as a key player in the neuropathology of HAND and HIV encephalitis (HIVE). Ongoing studies have suggested that B18R, a novel IFNα inhibitor, can alleviate HIVE pathology.
  Aims: We..

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